DTI-TK

Diffusion Tensor Imaging ToolKit

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References

Unbiased longitudinal DTI analysis (NEW!!!)

  • The unbiased longitudinal DTI spatial alignment algorithm and ROI-based analysis
Keihaninejad S, Zhang H, Ryan N, Malone I, Cardoso M, Modat M, Cash D, Fox N, Ourselin S. An unbiased longitudinal analysis framework for tracking white matter changes using diffusion tensor imaging with application to Alzheimer's disease, NeuroImage, 72:153-63, May 2013 PMID: 23370057. http pdf

Tensor-based DTI registration

  • The high-dimensional tensor-based DTI registration algorithm
Zhang, H., Avants, B.B, Yushkevich, P.A., Woo, J.H., Wang, S., McCluskey, L.H., Elman, L.B., Melhem, E.R., Gee, J.C., High-dimensional spatial normalization of diffusion tensor images improves the detection of white matter differences in amyotrophic lateral sclerosis, IEEE Transactions on Medical Imaging, 26(11):1585-1597, November 2007. PMID: 18041273. http pdf
  • The original piecewise-affine tensor-based DTI registration algorithm at the core of DTI-TK
Zhang, H., Yushkevich, P.A., Alexander, D.C., Gee, J.C., Deformable registration of diffusion tensor MR images with explicit orientation optimization, Medical Image Analysis, 10(5):764-785, October 2006. PMID: 16899392. http pdf

Population-based DTI atlas construction

  • The template construction algorithm
Zhang, H., Yushkevich, P.A., Rueckert, D., Gee, J.C., Unbiased white matter atlas construction using diffusion tensor images, MICCAI 2007, Lecture Notes in Computer Science, Volume 4792/2007, 211-218, October 2007. PMID: 18044571. http pdf
  • The computational aging DTI template with support for tract-specific analysis
Zhang, H., Yushkevich, P.A., Rueckert, D., Gee, J.C., A computational white matter atlas for aging with surface-based representation of fasciculi, International Workshop on Biomedical Image Registration, 6204, Lecture Notes in Computer Science, 83-90, July 2010 http
  • The computational primate DTI template
Adluru N, Zhang H, Fox AS, Shelton SE, Ennis CM, Bartosic AM, Oler JA, Tromp do PM, Zakszewski E, Gee JC, Kalin NH, Alexander AL. A diffusion tensor brain template for rhesus macaques, NeuroImage 2012 http

Tract-specific analysis

  • The original algorithm for quantifying tissue microstructure
Yushkevich, P.A., Zhang, H., Simon, T.J., Gee, .J.C., Structure-specific statistical mapping of white matter tracts, NeuroImage. 2008 Jun; 41(2):448-61 http
  • The algorithm for quantifying tract size as well as its microstructure
Zhang, H., Awate, S.P., Das, S.R., Woo, J.H., Melhem, E.R., Gee, J.C., Yushkevich, P.A., A tract-specific framework for white matter morphometry combining macroscopic and microscopic tract features, Medical Image Analysis, 14(5), October 2010 http
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