Diffusion Tensor Imaging ToolKit



Publications used DTI-TK


  1. Genc S, Steward C E et al. Short-term white matter alterations in Alzheimer's disease characterised by diffusion tensor imaging, Journal of Magnetic Resonance Imaging 2015. (link)
  2. Jirjis M B, Vedantam A et al. Severity of spinal cord injury influences diffusion tensor imaging of the brain, Journal of Magnetic Resonance Imaging 2015. (link)
  3. Kennis M, Van Rooij S J H et al. Treatment Outcome-Related White Matter Differences in Veterans with Posttraumatic Stress Disorder, Neuropsychopharmocology 2015. (link)
  4. Kochunov P, Jahanshad N et al. Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data, NeuroImage 2015. (link)
  5. Liu C, Tian X et al. Rhesus monkey brain development during late infancy and the effect of phencyclidine: A longitudinal MRI and DTI study, NeuroImage 2015. (link)
  6. Mahoney C, Simpson I et al. Longitudinal diffusion tensor imaging in frontotemporal dementia, Annals of Neurology 2015 (link)
  7. Nenadic I, Güllmar D et al. Brain structure in narcissistic personality disorder: A VBM and DTI pilot study, Psychiatric Research: Neuroimaging 2015 (link)
  8. Poudel G R, Stout J C et al. Longitudinal change in white matter microstructure in Huntington's disease: The IMAGE-HD study, Neurobiology of Disease 2015 (link)
  9. Thomas C, Avram A et al. Diffusion MRI properties of the human uncinate fasciculus correlate with the ability to learn visual associations, Cortex 2015. (link)
  10. Travers B G, Tromp D P M et al. Atypical development of white matter microstructure of the corpus callosum in males with autism: a longitudinal investigation, Molecular Autism 2015. (link)
  11. Ye C, Yang Z et al. Segmentation of the Cerebellar Peduncles Using a Random Forest Classifier and a Multi-object Geometric Deformable Model: Application to Spinocerebellar Ataxia Type 6, Neuroinformatics 2015. (link)


  1. Adluru N, Destiche D J et al. White matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer’s disease, NeuroImage Clinical 2014 (link)
  2. Bach M, Laun FB et al. Methodological considerations on tract-based spatial statistics (TBSS), NeuroImage 2014 (link)
  3. Barona-Gracia J. Comparison of Methodologies for Creation of White Matter Fiber Tract Atlases, San Diego State University Dissertation 2014. (link)
  4. Buijink A W G, Caan M W A et al. Structural changes in cerebellar outflow tracts after thalamotomy in essential tremor, Parkinsonism and Related Disorders 2014. (link)
  5. Chen H, Mei H et al. Visualizing Differences of DTI Fiber Models Using 2D Normalized Embeddings, IEEE Pacific Visualisation Symposium 2014 (link)
  6. Cole J, Farmer R E et al. Test-Retest Reliability of Diffusion Tensor Imaging in Huntington’s Disease, PLoS Currents 2014. (link)
  7. Davenport E M, Whitlow C T et al. Abnormal White Matter Integrity Related to Head Impact Exposure in a Season of High School Varsity Football, Journal of Neurotrauma 2014 (link)
  8. Evangelou I, Serag A et al. Optimised methodology for neonatal diffusion tensor imaging processing and study-specific template construction, IEEE Engineering in Medicine and Biology Society 2014. (link)
  9. Garaci F, Toschi N et al. Diffusion tensor imaging in SPG11- and SPG4-linked hereditary spastic paraplegia, International Journal of Neuroscience 2014. (link)
  10. Gupta A, Poe M D et al. Regional differences in fiber tractography predict neurodevelopmental outcomes in neonates with infantile Krabbe disease, NeuroImage Clinical 2014. (link)
  11. Hatton S N, Lagopoulos J et al. Short Association Fibres of the Insula-Temporoparietal Junction in Early Psychosis: A Diffusion Tensor Imaging Study, PLoS One 2014. (link)
  12. Kamnaksh A, Budde M D et al. Diffusion Tensor Imaging Reveals Acute Subcortical Changes after Mild Blast-Induced Traumatic Brain Injury, Scientific Reports 2014. (link)
  13. Kim J, Adluru N et al. Multivariate General Linear Models (MGLM) on Riemannian Manifolds with Applications to Statistical Analysis of Diffusion Weighted Images, CVPR 2014. (link)
  14. Kim J, Adluru N et al. Canonical Correlation Analysis on Riemannian Manifolds and Its Applications, ECCV 2014. (link)
  15. Kolbe S C, Kilpatrick T J et al. Inhibitory saccadic dysfunction is associated with cerebellar injury in multiple sclerosis, Human Brain Mapping 2014. (link)
  16. Kunz N, Zhang H et al. Assessing white matter microstructure of the newborn with multi-shell diffusion MRI and biophysical compartment models, NeuroImage 2014 (link)
  17. Lally P, Price D L et al. Neonatal Encephalopathic Cerebral Injury in South India Assessed by Perinatal Magnetic Resonance Biomarkers and Early Childhood Neurodevelopmental Outcome, PLoS One 2014. (link)
  18. Liu M, Chen Z et al. Disrupted anatomic white matter network in left mesial temporal lobe epilepsy, Epilepsia 2014. (link)
  19. Liu X, Yang Y et al. Reproducibility of diffusion tensor imaging in normal subjects: an evaluation of different gradient sampling schemes and registration algorithm, Neuroradiology 2014. (link)
  20. Maier-Hein KH, Westin CF et al. Widespread white matter degeneration preceding the onset of dementia, Alzheimer's & Dementia 2014. (link)
  21. Nenadic I, Gullmar D et al. Brain structure in narcissistic personality disorder: A VBM and DTI pilot study, Psychiatry Research: NeuroImage 2014 (link)
  22. Powers JP, Massimo L et al. White matter disease contributes to apathy and disinhibition in behavioral variant frontotemporal dementia, Cognitive and Behavioral Neurology 2014. (link)
  23. Racine AM, Adluru N et al. Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: A multimodal imaging investigation, Neuroimage Clinical 2014. (link)
  24. Shaw P, Sudre G et al. White Matter Microstructure and the Variable Adult Outcome of Childhood Attention Deficit Hyperactivity Disorder, Neuropsychopharmacology 2014 (link)
  25. Stemper B D, Shah A S et al. Head Rotational Acceleration Characteristics Influence Behavioral and Diffusion Tensor Imaging Outcomes Following Concussion, Annals of Biomedical Engineering 2014 (link)
  26. Timmers I, Zhang H et al. White matter microstructure pathology in classic galactosemia revealed by neurite orientation dispersion and density imaging, Journal of Inherited Metabolic Disease 2014 (link)
  27. Travers BG, Bigler ED et al. Longitudinal processing speed impairments in males with autism and the effects of white matter microstructure, Neuropsychologia 2014. (link)
  28. Treit S, Chen Z et al. White matter correlates of cognitive inhibition during development: A diffusion tensor imaging study, Neuroscience 2014. (link)
  29. Varentsova A, Zhang S, and Arfanakis K. Development of a high angular resolution diffusion imaging human brain template, Neuroimage 2014. (link)
  30. Woo J H, Wang S et al. Linear Associations between Clinically Assessed Upper Motor Neuron Disease and Diffusion Tensor Imaging Metrics in Amyotrophic Lateral Sclerosis, PLoS One 2014 (link)
  31. Zhang S and Arfanakis K. White Matter Segmentation Based on a Skeletonized Atlas: Effects on Diffusion Tensor Imaging Studies of Regions of Interest, Journal of Magnetic Resonance Imaging 2014. (link)


  1. Adluru N, Hanlon BM, Lutz A, Lainhart JE, Alexander AL, Davidson RJ. Penalized likelihood phenotyping: unifying voxelwise analyses and multi-voxel pattern analyses in neuroimaging, Neuroinformatics 2013 (link)
  2. Adluru N, Zhang H, Tromp DPM, Alexander AL. Effects of DTI spatial normalization on white matter tract reconstructions, SPIE 2013 (link)
  3. Bach M, Stieltjes B, Laun FB, Leemans A, Fritzsche KH. Voxel Misassignments and Their Consequences in DTI Skeleton-Based Group Analyses, ISMRM 2013 (link)
  4. Budde MD, Shah A, McCrea M, Cullinan WE, Pintar FA, Stemper BD (2013) Primary blast traumatic brain injury in the rat: relating diffusion tensor imaging and behavior, Front. Neurol. 4:154. (link)
  5. Cabeen R, Bastin M, Laidlaw D. Estimating Constrained Multi-fiber Diffusion MR Volumes by Orientation Clustering, MICCAI 2013 (link)
  6. Cabeen R, Laidlaw D, Bastin M. Atlas-based multi-direction tractography using tensor registration and orientation statistics, OHBM 2013 (link)
  7. Chen Z, Liu M, Zhang H, Beaulieu C. Mapping patterns of white matter maturation in human brain using tract-specific analysis, OHBM 2013 (link)
  8. Duarte-Carvajalino J M, Sapiro G, Harel N, Lenglet C. A Framework for Linear and Non-Linear Registration of Diffusion-Weighted MRIs Using Angular Interpolation. Frontiers in Brain Imaging Methods 2013 (link)
  9. Duclap D, Schmitt B, Lebois A, Guevara P, Zhang H, Dos Santos CL, Le Bihan D, Mangin J-F, Poupon C. Towards a super-resolution CONNECT/ARCHI atlas of the white matter connectivity, ISMRM 2013 (link)
  10. Gupta A, Toews M, Janardhana R, Rathi Y, Gilmore J, Escolar M, Styner M. Fiber feature map based landmark initialization for highly deformable DTI registration, SPIE 2013 (link)
  11. Hanson JL, Adluru N, Chung MK, Alexander AL, Davidson RJ, Pollak SD. Early Neglect is Associated With Alterations in White Matter Integrity and Cognitive Functioning, Child Development 2013 (link)
  12. Keihaninejad S, Zhang H, Ryan N, Malone I, Cardoso M, Modat M, Cash D, Fox N, Ourselin S. An unbiased longitudinal analysis framework for tracking white matter changes using diffusion tensor imaging with application to Alzheimer's disease, NeuroImage 2013 (link)
  13. Kunz N, Zhang H, Assaf Y, Lazeyras F, Alexander D, Huppi P. Brain microstructure assessed by CHARMED and NODDI in the newborn, ISMRM 2013 (link)
  14. Lao Y, Dion LA, Yepes F, Gilbert G, Bouchard M, Amour D S, Lepore N. Tract Specific Analysis reveals the impact of childhood manganese exposure on the corpus callosum, ISMRM 2013 (link)
  15. Lebois A, Duclap D, Schmitt B, Dos Santos CL, Guevara P, Zhang H, Le Bihan D, Mangin J-F, Poupon C. Towards Probabilistic Atlases of the T1/T2 Relaxation Times from the CONNECT/ARCHI Database, ISMRM 2013 (link)
  16. Lyksborg M, Dyrby T B, Sorensen P S, Blinkenberg M, Siebner H R, Alexander D, Larsen R, Zhang H. Tract-oriented statistical group comparison of diffusion in sheet-like white matter, ISBI 2013 (link)
  17. Powers J P, McMillan C T, Brun C C, Yushkevich P A, Zhang H, Gee J C, and Grossman M. White matter disease correlates with lexical retrieval deficits in primary progressive aphasia, Frontiers in Neurology 2013. (link)
  18. Ryan NS, Keihaninejad S, Shakespeare T, Lehmann M, Crutch SJ, Malone IB, Thornton JS, Mancini L, Hyare H, Yousry T, Ridgway GR, Zhang H, Modat M, Alexander DC, Rossor MN, Ourselin S, Fox NC. MRI evidence for presymptomatic change in thalamus and caudate in familial Alzheimer’s disease, Brain 2013 (link)
  19. Schmitt B, Duclap D, Lebois A, Guevara P, Zhang H, Assaf Y, Poupon F, Riviere D, Cointepas Y, Le Bihan D, Mangin J-F, Poupon C. A Novel Probabilistic Connectivity Atlas for the Human Connectome : The CONNECT/ARCHI Atlas, ISMRM 2013 (link)
  20. Taquet M, Scherrer B et al. A Mathematical Framework for the Registration and Analysis of Multi-Fascicle Models for Population Studies of the Brain Microstructure, IEEE TMI 2013 (link)
  21. Wang Q, Yap P-T, Wu G, Shen D. Diffusion tensor image registration using hybrid connectivity and tensor features, HBM 2013 (link)
  22. Wang Y, Li G, Ahn M, Nie J, Zhu H, Guo L. Mapping longitudinal cerebral cortex development using diffusion tensor imaging, SPIE 2013 (link)
  23. Yeh P-H, Wang B, Oakes TR, French LM, Pan H, Graner J, Liu W, Riedy G, Postconcussional Disorder and PTSD Symptoms of Military-Related Traumatic Brain Injury Associated With Compromised Neurocircuitry, Human Brain Mapping 2013 (link)
  24. Yushkevich P A, Zhang H. Deformable Modeling Using a 3D Boundary Representation with Quadratic Constraints on the Branching Structure of the Blum Skeleton, IPMI 2013 (link)
  25. Zakszewski E, Adluru N, Kalin N, Alexander AL. A Digital White Matter Atlas of the Rhesus Macaque Brain, ISMRM 2013 (link)
  26. Zhang S and Arfanakis K. Role of standardized and study-specific human brain diffusion tensor templates in inter-subject spatial normalization, Journal of Magnetic Resonance Imaging 2013 (link)
  27. Zhang S and Arfanakis K. Development of a Comprehensive Digital Human Brain Atlas, ISMRM 2013 (link)


  1. Adluru N, Zhang H, Fox AS, Shelton SE, Ennis CM, Bartosic AM, Oler JA, Tromp do PM, Zakszewski E, Gee JC, Kalin NH, Alexander AL. A diffusion tensor brain template for rhesus macaques, NeuroImage 2012 (link)
  2. Adluru N, Ennis CM, Davidson RJ, Alexander AL. Max Margin General Linear Modeling for Neuroimage Analyses, IEEE Workshop MMBIA 2012 (link)
  3. Ashtari M and Cyckowski L. Brain Development During Adolescence, Handbook of Growth and Growth Monitoring in Health and Disease 2012 (link)
  4. Ashtari M and Cyckowski L. Vulnerability of Adolescent Brain Growth to Cannabis, Handbook of Growth and Growth Monitoring in Health and Disease 2012 (link)
  5. Buch ER, Modir Shanechi A, Fourkas AD, Weber C, Birbaumer N, Cohen LG. Parietofrontal integrity determines neural modulation associated with grasping imagery after stroke, Brain 2012 (link)
  6. Carletti F, Woolley JB, Bhattacharyya S, Perez-Iglesias R, Fusar Poli P, Valmaggia L, Broome MR, Bramon E, Johns L, Giampietro V, Williams SC, Barker GJ, McGuire PK. Alterations in White Matter Evident Before the Onset of Psychosis, Schizophr Bull 2012 (link)
  7. Carletti F, Marquand A, Woolley J, Perez-Iglesias R, Broome M, Johns L, Bramon E, Williams S, McGuire P, Barker G. White matter pattern classification in the At-Risk Mental State for psychosis, OHBM 2012 (link)
  8. Geng X, Prom­Wormley EC, Perez J, Kubarych T, Styner M, Lin W, Neale MC and Gilmore JH. White Matter Heritability Using Diffusion Tensor Imaging in Neonatal Brains, Twin Research and Human Genetics 2012 (link)
  9. Gupta A, Escolar M, Dietrich C, Gilmore J, Gerig G, and Styner M. 3D Tensor Normalization for Improved Accuracy in DTI Tensor Registration Methods, Workshop on Biomedical Image Registration 2012 (link)
  10. Irfanoglu MO, Walker L, Sarlls J, Marenco S, Pierpaoli C. Effects of image distortions originating from susceptibility variations and concomitant fields on diffusion MRI tractography results, NeuroImage 2012 (link)
  11. Keihaninejad S, Zhang H, Ryan N, Malone I, Frost C, Cardoso M, Modat M, Mancini L, Thornton J, Cash D, Ourselin S, Fox N. Longitudinal changes in fiber tract integrity in Alzheimer's disease: A serial diffusion tensor imaging study, Alzheimer's & Dementia 2012 (link)
  12. Keihaninejad S, Zhang H, Shakespeare T, Ryan N, Malone I, Frost C, Cardoso M, Modat M, Lehmann M, Mancini L, Thornton J, Warren J, Cash D, Crutch S, Ourselin S, Fox N. Longitudinal changes in fiber tract integrity in posterior cortical atrophy: Serial diffusion tensor imaging, Alzheimer's & Dementia 2012 (link)
  13. Keihaninejad S, Zhang H, Ryan N, Malone I, Frost C, Cardoso M, Modat M, Mancini L, Thornton J, Cash D, Ourselin S, Fox N. White matter tract changes in mild-to-moderate Alzheimer's disease revealed by tensor-based registration analyses of diffusion tensor imaging, Alzheimer's & Dementia 2012 (link)
  14. Kolbe SC, Marriott M, Walt Av, Fielding J, Klistorner A, Mitchell PJ, Butzkueven H, Kilpatrick TJ, Egan GF. Diffusion tensor imaging correlates of visual impairment in multiple sclerosis and chronic optic neuritis, Invest Ophthalmol Vis Sci 2012 (link)
  15. Loh KB, Ramli N, Tan LK, Roziah M, Rahmat K and Ariffin H. Quantification of diffusion tensor imaging in normal white matter maturation of early childhood using an automated processing pipeline, European Radiology 2012 (link)
  16. McAllister TW, Ford JC, Ji S, Beckwith JG, Flashman LA, Paulsen K, Greenwald RM. Maximum principal strain and strain rate associated with concussion diagnosis correlates with changes in corpus callosum white matter indices, Ann Biomed Eng 2012 (link)
  17. McMillan CT, Brun C, Siddiqui S, Churgin M, Libon D, Yushkevich PA, Zhang H, Boller A, Gee J, Grossman M. White matter imaging contributes to the multimodal diagnosis of frontotemporal lobar degeneration, Neurology 2012 (link)
  18. Tariq M, Schneider T, Alexander DC, Wheeler-Kingshott C, Zhang H. Scan-rescan reproducibility of neurite microstructure estimates using NODDI, Medical Image Understanding and Analysis 2012 (link)
  19. Tustison NJ, Avants BB, Cook PA, Kim J, Whyte J, Gee JC, Stone JR. Logical circularity in voxel-based analysis: Normalization strategy may induce statistical bias, Human Brain Mapping 2012 (link)
  20. Travers BG, Adluru N, Ennis C, Tromp DPM, Destiche D, Doran S, Bigler ED, Lange N, Lainhart JE, Alexander AL. Diffusion Tensor Imaging in Autism Spectrum Disorder: A Review, Autism Research 2012 (link)
  21. Tromp DPM, Fox AS, Oler JA, Adluru N, Davidson RJ, Alexander AL, Kalin NH. Cortisol predicts increased internal capsule integrity in a large sample of non-human primates, European Journal of Psychotraumatology 2012 (link)
  22. Walker L, Curry M, Nayak A, Lange N, Pierpaoli C; and the Brain Development Cooperative Group. A framework for the analysis of phantom data in multicenter diffusion tensor imaging studies, Human Brain Mapping 2012 (link)
  23. Walker L, Gozzi M, Lenroot R, Thurm A, Behseta B, Swedo S, Pierpaoli C. Diffusion Tensor Imaging in Young Children with Autism: Biological Effects and Potential Confounds, Biological Psychiatry 2012 (link)
  24. Zakszewski E, Fox A S, Oler J, Adluru N, Converse A K, Moirano J M, Kalin N, and Alexander A L. Comparison of probabilistic diffusion tensor tractography with histological tracer studies and RSFC in the rhesus macaque, ISMRM 2012 (link)
  25. Zuo N, Cheng J, Jiang T. Diffusion magnetic resonance imaging for Brainnetome: A critical review, Neuroscience Bulletin 2012 (link)


  1. Caan MW, van Vliet LJ, Majoie CB, van der Graaff MM, Grimbergen CA, Vos FM. Nonrigid point set matching of white matter tracts for diffusion tensor image analysis, IEEE Trans Biomed Eng 2011 (link)
  2. Gan L and Agam G. Efficient nonlinear DTI registration using DCT basis functions, IEEE CVPRW 2011.
  3. Hasan KM, Walimuni IS, Abid H, Hahn KR. A review of diffusion tensor magnetic resonance imaging computational methods and software tools, Comput Biol Med 2011 (link)
  4. Rafael-Patino J, Ramirez-Manzanares A, Rivera M. Estimation of Anisotropic Water Diffusion Indexes on Axon Bundle Crossings, MICAI 2011 (link)
  5. Ramirez-Manzanares A, Cook PA, Hall M, Ashtari M, Gee JC. Resolving axon fiber crossings at clinical b-values: an evaluation study, Med Phys 2011 (link)
  6. Rink C, Christoforidis G, Khanna S, Peterson L, Patel Y, Khanna S, Abduljalil A, Irfanoglu O, Machiraju R, Bergdall VK, Sen CK. Tocotrienol vitamin E protects against preclinical canine ischemic stroke by inducing arteriogenesis, J Cereb Blood Flow Metab 2011 (link)
  7. Walker L, Chang LC, Koay CG, Sharma N, Cohen L, Verma R, Pierpaoli C. Effects of physiological noise in population analysis of diffusion tensor MRI data, NeuroImage 2011 (link)
  8. Wang Y, Gupta A, Liu Z, Zhang H, Escolar ML, Gilmore JH, Gouttard S, Fillard P, Maltbie E, Gerig G, Styner M. DTI registration in atlas based fiber analysis of infantile Krabbe disease, NeuroImage 2011 (link)
  9. Wee CY, Yap PT, Li W, Denny K, Browndyke JN, Potter GG, Welsh-Bohmer KA, Wang L, Shen D. Enriched white matter connectivity networks for accurate identification of MCI patients, NeuroImage 2011 (link)
  10. Yap PT, Chen Y, An H, Yang Y, Gilmore JH, Lin W, Shen D. SPHERE: SPherical Harmonic Elastic REgistration of HARDI data, NeuroImage 2011 (link)
  11. Zhang S, Peng H, Dawe RJ, Arfanakis K. Enhanced ICBM diffusion tensor template of the human brain, NeuroImage 2011 (link)


  1. Avants BB, Cook PA, Ungar L, Gee JC, Grossman M. Dementia induces correlated reductions in white matter integrity and cortical thickness: a multivariate neuroimaging study with sparse canonical correlation analysis, NeuroImage 2010 (link)
  2. Ingalhalikar M , Yang JZ, Davatzikos C, Verma R. DTI-DROID: Diffusion tensor imaging-deformable registration using orientation and intensity descriptors, Intl J of Imaging Sys Tech 2010
  3. Motwani K, Adluru N, Hinrichsts C, Alexander A, Singh V. Epitome driven 3-D Diffusion Tensor image segmentation: on extracting specific structures, Adv Neural Inf Process Syst 2010 (link)
  4. Patel V, Dinov ID, Van Horn JD, Thompson PM, Toga AW. LONI MiND: metadata in NIfTI for DWI, NeuroImage 2010 (link)


  1. Ramirez-Manzanares A, Rivera M, Gee JC. Depicting axon fibers on a diffusion phantom by means of hybrid DBF-DT data, MICCAI Workshop Fibre Cup 2009 (link)


  1. Ramirez-Manzanares A, Zhang H, Rivera M, Gee JC. Robust regularization for the estimation of intra-voxel axon fiber orientations, IEEE CVPRW 2008 (link)
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