DTI-TK Home Page

What is DTI-TK?

DTI-TK is a spatial normalization and atlas construction toolkit optimized for examining white matter morphometry using DTI data. A 2011 study published in NeuroImage ranks DTI-TK the top-performing tool in its class.

• open standard-based file IO support: NIfTI format for scalar, vector and tensor image volumes
• tool chains for manipulating tensor image volumes: resampling, smoothing, warping, registration & visualization
• pipelines for WM morphometry: spatial normalization & atlas construction for population-based studies
• built-in cluster-computing support: support for open source Sun Grid Engine (SGE)
• Interoperability with other popular DTI tools: AFNI, Camino, FSL & DTIStudio
• Interoperability with ITK-SNAP: support multi-modal visualization and segmentation

How Much Does it Cost?

DTI-TK is free software, provided under ------ the General Public License. DTI-TK binaries are provided free of charge for academic or commercial use. Development and continued maintenance of DTI-TK have been made possible by grants from the U.S. National Institutes of Health and by the generous time investments from members of the DTI-TK developer community.

Since DTI-TK is free, there's no technical support number to call. We do our best to answer questions on the mailing lists in a timely manner, but we count on other users to offer answers as well. Often, DTI-TK development is done on a volunteer basis. Please keep that in mind when you use DTI-TK.

Who Develops DTI-TK?

DTI-TK has been developed as part of Gary Zhang's Ph.D. thesis at Penn Image Computing and Science Laboratory (PICSL), University of Pennsylvania, under the supervision of Dr. James C Gee. Several members of PICSL now help maintain and develop DTI-TK.

What Can DTI-TK do for Me?

DTI-TK is a very convenient tool that allows you to register, analyze and visualize DTI images very easily. If you know how to use very simple unix command lines, then using DTI-TK is very easy!

What can't DTI-TK do for Me?

DTI-TK does not replicate the core functionalities of many existing popular DTI packages, such as CAMINO or DTIStudio but is designed to allow users of these existing tools to leverage DTI-TK in a pain-free way. The Interoperability page gives detailed descriptions of how DTI-TK enables the seamless integration of DTI-TK with your favorite DTI tool.

What is not supported by DTI-TK?

• tensor reconstruction -constructing diffusion tensor images from raw diffusion-weighted images and related preprocessing support
• Probabilistic fiber tractography

How Can I Contribute?

You can help make DTI-TK better in two ways:

• If you use DTI-TK and report its successes and failures, you will help identify bugs and missing features. Use the 'Bugs' link at the top of this page to report bugs.
• If you are a software developer, you can contribute to DTI-TK as it is an open source application. To become a developer, join us on SourceForge.